To determine if sulforaphane supplements would be well tolerated and might alter some of the epigenetic mechanisms involved in cancer.
Test subject: Placebo-controlled trial, 54 women with abnormal mammograms
They were given either a placebo or supplements that provided sulforaphane. The amount of sulforaphane they received would equate to about one cup of broccoli sprouts per day, if eaten as a food.
Findings and Conclusions
- Decrease in markers of cell growth, which means these compounds may help slow cancer cell growth.
- Studies have found that women with a high intake of cruciferous vegetables, such as broccoli, cauliflower, cabbage or kale, have a decreased risk of breast cancer.
- The intake of sulforaphane did reduce HDAC activity, as well as cancer cell growth. Journal Cancer Prevention Research
Researchers said additional studies are needed to evaluate dose responses, work with larger populations, and examine the responses of other relevant molecular targets to either foods or supplements containing sulforaphane.
Study was conducted by the researcher of Oregon State University (OSU) and the Oregon Health & Science University.
Information by Philippine News Agency